Dr. Ernstoff is Professor of Medicine, Geisel School of Medicine; and Staff Physician at the Lerner School of Medicine at the Cleveland Clinic. He is currently the Geisel PI on the Cancer Immunotherapy Trial Network and is on the executive council of the Cytokine Working Group. Dr. Ernstoff is also a member of the Alliance Experimental Therapeutics Program. In 2016, Dr. Ernstoff assumed the role of Professor and Chair, Department of Medicine, Senior Vice President for Clinical Investigation. The Katherine Anne Gioia Chair of Medicine, Roswell Park Cancer Institue and Professor and Chief of the Section of Oncology at the University of Buffalo.